The origins of stem cells for use in the biosciences and in cosmetics are extremely brutal and should be illegal. Sandra Bullock explains it better than I could:
https://youtu.be/PwO3TEj9-5g
That can't be good. Life cycle of a human egg is organized around preserving mitochondria to be as young and fresh as possible across generations. Using adult cell, even a stem cell to make an egg probably gives it mitochondrial damage that usually takes hundreds of human generations to accumulate.
Can you point me to anything about mitochondrial transplants? I'd love to see bat mitochondria transplanted into other mammals. They must have really superior ones given the energy expenditures needed to support flight and their long lifespans.
When the damage accumulates across generations the natural selection has opportunity to weed out particularly harmful instances. You can get a feeling for how important avoiding the mitochondrial damage is and how hard it is to mitigate, by looking at how fiercely the reproductive process protects them from aging.
Guess the japanese excel at micromanaging. Although one could
say that the research here in the article is more epic than
Shinya's discovery, but I remember having watched one of his
presentation and it convinced me of pure epicness, if you
understand how his team found the "Yamanaka factors". That
was by human (work) consistency. About as epic as
Christiane Nüsslein-Volhard and her mutant screens, that also
involved tons of micro-experiments.
Can we stop adding unnecessary JS to website to stop global warming by calculating AND ALTERING SCROLL?
Firefox on Samsung S23, not exactly a new or a powerful phone but rendered it fine.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7169912/
Shinya Yamanaka created iPSPs in 2009:
https://en.wikipedia.org/wiki/Shinya_Yamanaka
Guess the japanese excel at micromanaging. Although one could say that the research here in the article is more epic than Shinya's discovery, but I remember having watched one of his presentation and it convinced me of pure epicness, if you understand how his team found the "Yamanaka factors". That was by human (work) consistency. About as epic as Christiane Nüsslein-Volhard and her mutant screens, that also involved tons of micro-experiments.